What are your feelings about States rights vs Federal Government?

Here in California, we ped a Medical Marajuana law(s) that made use of gr legal for medical purposes...this drug works well with little or no side effects for those with nausia from several source (chemotherapy is but one), and glaucoma. YET the Federal Govenment is constantly stepping into our business as NARCS! Where does the Federal Government get off ignoring a States right to do as they please, when voting by the majority say YES! The Federal Government insists that you pay full price for drugs, State seen to have no problem with your ordering from Canada. Is it time we rose up as a unit as said, "enough is enough" of Federal meddling in State's rights to chose how to run their states? I, for one, do not trust the Federal Government any farther than I can throw it...this Administrations has proven I am right...what ar your thoughts? Are you willing to take time to write your congressmen and senators about your feelings, or do we allow lobbiest to run our country?